Intraoperative Touch Imprint Cytology of Brain Neoplasms: A Useful High-Diagnostic Tool in 93 Consecutive Cases; Differential Diagnoses, Pitfalls, and Traps

Figure 5

Adult-type diffuse glioma (high-grade glioma). (a–c) In touch imprint cytology, oval-elongated nuclei with marked atypia, fibrillar cytoplasmic processes, and increased cellularity are observed (H&E, ×100, ×400). (d, e) Microvascular proliferation and infarct-like necrosis are observed in paraffin sections (H&E, ×100). (f) GFAP is diffusely positive in immunohistochemical studies (×100).