Identification of a 16-MTGs Prognostic Signature in Diffuse Large B-Cell Lymphoma

Figure 4

Construction and verification of the prognostic 16-MTGs signature in GEO cohorts. The time-dependent ROC curves of the prognostic genes signature in GSE11318 training cohort ((a), according to single gene). The calibration plots for 1-, 3-, and 5-year OS according to 16 DE-MTGs signature in GSE11318 training cohort (b). The error lines in the figure represent the standard deviation of the true survival times of different patients with the same predicted survival time. Decision curve analysis for two risk signatures for diffuse large B-cell lymphoma (c). Kaplan–Meier OS curves of the gene signature in GSE11318 training cohort (d). The differential expression of 16 genes between low-risk and high-risk tumor tissue (e). The legends at the top of the image showed the results of analyzing the differences between the high and low risk groups using T-tests.

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