Research Article
The Clinical and Pathological Effects of Serum C3 Level and Mesangial C3 Intensity in Patients with IgA Nephropathy
Table 5
C3 deposition in mesangial area and laboratory examination indexes.
| Laboratory examination | Negative | Weakly positive | Strongly positive | P Value |
| FPG (mmol/L) | 5.32 ± 1.02 | 5.03 ± 0.84 | 5.16 ± 0.55 | 0.107 | BUN (mmol/L) | 5.56 ± 2.15 | 6.04 ± 2.69 | 7.4 ± 3.04 | 0.003 | UA (umol/L) | 363.63 ± 104.07 | 382.87 ± 129.73 | 435.65 ± 125.5 | 0.016 | Scr (umol/L) | 79.89 ± 30.7 | 91.27 ± 37.21 | 114.1 ± 48.63 | 0.001 | eGFR (mL/min/1.73 m2) | 105.91 ± 43.39 | 94.79 ± 43.14 | 75.32 ± 38.85 | 0.003 | Alb (g/L) | 36.14 ± 9.83 | 36.56 ± 8.04 | 38.1 ± 7.04 | 0.552 | TC (mmol/L) | 6.27 ± 2.61 | 6.11 ± 2.48 | 6.06 ± 1.69 | 0.900 | LDL-C (mmol/L) | 4.01 ± 2.31 | 3.85 ± 1.86 | 3.83 ± 1.32 | 0.873 | HDL (mmol/L) | 1.2 ± 0.35 | 1.32 ± 0.48 | 1.27 ± 0.44 | 0.280 | TG (mmol/L) | 2.31 ± 1.33 | 1.87 ± 1.01 | 2.57 ± 2.31 | 0.098 | Serum IgA (mg/L) | 336.32 ± 167.42 | 334 ± 126.01 | 352.94 ± 115.4 | 0.813 | Serum IgG (mg/L) | 1055.91 ± 409.46 | 933.16 ± 337.26 | 950.94 ± 412.63 | 0.192 | Serum IgM (mg/L) | 114.93 ± 51.41 | 113.1 ± 58.61 | 104.45 ± 42.23 | 0.619 | Serum C3 (mg/dL) | 120.66 ± 24.9 | 105.23 ± 25.33 | 91.43 ± 27.32 | 0.001 | 24hUP (g/24 hr) | 3.73 ± 3.32 | 3.65 ± 2.83 | 3.08 ± 2.34 | 0.558 | IgA/C3 ratio | 2.91 ± 1.67 | 3.34 ± 1.41 | 4.31 ± 2.42 | 0.001 |
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Abbreviations. FPG, fasting plasma glucose; BUN, blood urea nitrogen; UA, uric acid level; Scr, serum creatinine; Alb, albumin; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterin; HDL, high-density lipoprotein cholesterin; TG, triglyceride; 24hUP, 24-hr urinary total protein, 24hUP.
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