Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE

<div>PDIA3P1 downregulation in PE placental tissues. (a) RT-qPCR analysis revealed diminished PDIA3P1 expression in PE placental tissues compared to normal tissues. (b) PDIA3P1 expression levels were assessed in trophoblast cell lines (HTR-8/SVneo, JAR, and JEG3) and the HUVEC cell line. (c) RT-qPCR analysis depicted PDIA3P1 expression in HTR-8/SVneo, JAR, and HUVEC cells transfected with a PDIA3P1-overexpressing plasmid. Relative PDIA3P1 expression in HTR-8/SVneo (d), JAR (e), and HUVEC (f) cells after PDIA3P1 siRNA transfection. 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Analytical Cellular Pathology

fig1

Figure 1

Figure 1: Downregulated PDIA3P1 lncRNA Impairs Trophoblast Phenotype by Regulating Snail and SFRP1 in PE 