Research Article
Seizures as Initial Presentation and Enduring Predisposition to Seizures in Autoimmune Encephalitis
Table 2
The characteristics of initial seizures in antibody-positive and antibody-negative AE patients.
| Variables | Antibody-positive AE (90, 60.8%) | Antibody-negative AE (58, 38.9%) | value |
| Seizure type at onset | | | | Generalized, (%) | 11 (12.2%) | 15 (25.9%) | 0.033 | Focal motor, (%) | 28 (31.1%) | 21 (36.2%) | 0.520 | Focal nonmotor, (%) | 6 (6.7%) | 8 (13.8%) | 0.148 | Focal to bilateral, (%) | 70 (77.8%) | 30 (51.7%) | 0.001 | Multiple seizure type, (%) | 25 (27.8%) | 15 (25.9%) | 0.798 | FBDS, (%) | 3 (3.3%) | 0 | 0.160 | Seizure frequency at onset | | | | Daily, (%) | 45 (50.0%) | 34 (58.6%) | 0.305 | Weekly, (%) | 20 (22.2%) | 10 (17.2%) | 0.462 | Monthly, (%) | 25 (27.8%) | 14 (24.1%) | 0.624 | Drug resistance to ASMs at onset, (%) | 28 (31.1%) | 15 (25.9%) | 0.492 | The number of received ASMs, median [IQR] | 2 [1-3] | 2 [1-3] | 0.411 |
|
|
Abbreviations: FBDS: faciobrachial dystonic seizures; ASMs: antiseizure medications.
|