Development of the RP-HPLC Method for Simultaneous Determination and Quantification of Artemether and Lumefantrine in Fixed-Dose Combination Pharmaceutical Dosage Forms

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left">Parameters</td><td class="align_center">Artemether</td><td class="align_center">Lumefantrine</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Slope (s)</td><td class="align_center">0.2296</td><td class="align_center">15.609</td></tr><tr><td class="align_left">SD</td><td class="align_center">0.5534</td><td class="align_center">0.3019</td></tr><tr><td class="align_left">LOD (<i>μ</i>g/mL)</td><td class="align_center">7.95</td><td class="align_center">0.064</td></tr><tr><td class="align_left">LOQ (<i>μ</i>g/mL)</td><td class="align_center">24.10</td><td class="align_center">0.193</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Limit of detection (LOD) and limit of quantification (LOQ).</div>

Advances in Pharmacological and Pharmaceutical Sciences

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Table 3

Table 3: Development of the RP-HPLC Method for Simultaneous Determination and Quantification of Artemether and Lumefantrine in Fixed-Dose Combination Pharmaceutical Dosage Forms 

Table 3 | Development of the RP-HPLC Method for Simultaneous Determination and Quantification of Artemether and Lumefantrine in Fixed-Dose Combination Pharmaceutical Dosage Forms 