Molecular Modelling and Dynamics Study of nsSNP in STXBP1 Gene in Early Infantile Epileptic Encephalopathy Disease

Figure 6

Radius of gyration for STXBP1 protein and its variants proteins for 5000 ps of molecular dynamic simulation. Color scheme: (a) wt-STXBP1 (black), S42P (red), and (L365V) magenta. (b) wt-STXBP1 (black), H103D (cyan), R235G (brown), L256P (yellow), R406C (grey), P335S (violet) and G544D (maroon). (c) wt-PIWIL1 (black), (R190W) blue, (D238E) orange, and (C354Y) green.

(a)

(b)

(c)