miR-1929-3p Overexpression Alleviates Murine Cytomegalovirus-Induced Hypertensive Myocardial Remodeling by Suppressing Ednra/NLRP3 Inflammasome Activation

Figure 1

MCMV infection raised BP and decreased the expression of miR-1929-3p in C57BL/6 mice. (a) Schematic of intervention here and in Figure 2 in the experimental group. (b) PCR analysis of the MCMV IE gene in the myocardium of C57BL/6 mice. (c) ELISA detection of IgG concentration in plasma. (d) ELISA detection of IgM concentration in plasma. (e) qRT-PCR analysis of miR-1929-3p expression in the myocardium. The value was normalized to the value observed with the control groups, which was set to 1: (f) SBP; (g) DBP; (h) MAP. The data are expressed as the (), , the MCMV groups vs. the age-matched control groups. , the MCMV 9-month groups vs. the control 7-month groups.

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