miR-1929-3p Overexpression Alleviates Murine Cytomegalovirus-Induced Hypertensive Myocardial Remodeling by Suppressing Ednra/NLRP3 Inflammasome Activation

Figure 7

miR-1929-3p overexpression decreased ET-1 and IL-1β activation in MCMV-infected mice. (a, c, e) ELISA detection of ET-1, IL-1β, and IL-18 concentration in plasma. (b, d, f) ELISA detection of ET-1, IL-1β, and IL-18 concentration in cardiac tissues. The data are expressed as the (), vs. the age-matched control groups. , the MCMV+miR-1929-3p groups vs. the age-matched MCMV groups. (g) A schematic model showing the essential role of miR-1929-3p and Ednra in MCMV-induced hypertensive cardiac remodeling.

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