Haematinic and Hepatoprotective Properties of Telfairia occidentalis Fruit Mesocarp on Phenylhydrazine-Induced Anaemia in Experimental Rats
Table 2
Detail of the experimental protocol and design.
Group
Description
Procedure
1
Nonanaemic control group containing six (6) rats
Rats in this group were solely given distilled water with feed from D0 to D8
2
Anaemic control group containing six (6) rats
Rats were given phenylhydrazine at 40 mg/kg b.wt for two days (D0 and D1) and distilled water with feed from D2 to D8
3
Control reference group containing six (6) rats
Rats were given phenyl hydrazine at 40 mg/kg b.wt for two days (D0 and D1) and 1 ml/kg b.wt of Astymin from D2 to D8
4
Anaemic test group containing six (6) rats given low dose of extract
Rats were given phenylhydrazine at 40 mg/kg b.wt for two days (D0 and D1) in order to induce anaemia. They were then treated with 600 mg/kg b.wt of the Telfairia occidentalis fruit mesocarp aqueous extract from D2 to D8
5
Anaemic test group containing six (6) rats given high dose of the extract
Rats were given phenylhydrazine at 40 mg/kg b.wt for two days (D0 and D1) in order to induce anaemia. They were then treated with 1000 mg/kg/b.wt of the Telfairia occidentalis fruit mesocarp aqueous extract from D2 to D8
D0 = day the experiment was started; D1 = first day after the start of the experiment; D2 = second day after the start of the experiment; D8 = eighth day after the start of the experiment (also the last day of the experiment).