Research Article

Haematinic and Hepatoprotective Properties of Telfairia occidentalis Fruit Mesocarp on Phenylhydrazine-Induced Anaemia in Experimental Rats

Table 2

Detail of the experimental protocol and design.

GroupDescriptionProcedure

1Nonanaemic control group containing six (6) ratsRats in this group were solely given distilled water with feed from D0 to D8
2Anaemic control group containing six (6) ratsRats were given phenylhydrazine at 40 mg/kg b.wt for two days (D0 and D1) and distilled water with feed from D2 to D8
3Control reference group containing six (6) ratsRats were given phenyl hydrazine at 40 mg/kg b.wt for two days (D0 and D1) and 1 ml/kg b.wt of Astymin from D2 to D8
4Anaemic test group containing six (6) rats given low dose of extractRats were given phenylhydrazine at 40 mg/kg b.wt for two days (D0 and D1) in order to induce anaemia. They were then treated with 600 mg/kg b.wt of the Telfairia occidentalis fruit mesocarp aqueous extract from D2 to D8
5Anaemic test group containing six (6) rats given high dose of the extractRats were given phenylhydrazine at 40 mg/kg b.wt for two days (D0 and D1) in order to induce anaemia. They were then treated with 1000 mg/kg/b.wt of the Telfairia occidentalis fruit mesocarp aqueous extract from D2 to D8

D0 = day the experiment was started; D1 = first day after the start of the experiment; D2 = second day after the start of the experiment; D8 = eighth day after the start of the experiment (also the last day of the experiment).