Haematinic and Hepatoprotective Properties of Telfairia occidentalis Fruit Mesocarp on Phenylhydrazine-Induced Anaemia in Experimental Rats
Table 4
Haematological indices and liver enzymes for the various rat groups at day 3.
Rat groups
RBC (106/L)
WBC (109/L)
Hb (g/dL)
PCV (%)
MCV (fL)
MCH (pg)
MCHC (g/dL)
AST (μ/L)
ALT (μ/L)
ALP (μ/L)
G1
5.35 ± 1.25
8.10 ± 0.60#a
15.45 ± 0.35#
46.30 ± 2.30#
85.85 ± 0.65#
24.70 ± 0.60#
43.55 ± 0.55#
51.90 ± 1.60#
26.95 ± 0.25#
120.00 ± 1.00#
G2
3.67 ± 0.24
5.30 ± 0.20a
13.05 ± 0.35a
40.50 ± 0.50
81.25 ± 0.95a
33.50 ± 0.40a
40.90 ± 0.60a
79.70 ± 1.10a
40.10 ± 0.40a
149.60 ± 1.00a
G3
3.92 ± 0.39
10.80 ± 0.10#
15.20 ± 0.70#
44.00 ± 1.00
85.65 ± 1.05#
25.75 ± 0.45#
44.00 ± 1.30#
50.75 ± 1.35#
25.55 ± 1.05#
118.50 ± 1.50#
G4
3.81 ± 0.45
8.55 ± 0.35#a
11.45 ± 0.35#a
40.00 ± 1.00
79.05 ± 0.85#a
33.70 ± 0.10a
41.75 ± 0.15
82.20 ± 0.40a
41.10 ± 0.20a
152.80 ± 0.20a
G5
2.95 ± 0.15
7.30 ± 0.30#a
11.05 ± 0.35#a
38.40 ± 0.40a
74.75 ± 0.55
30.75 ± 0.75#a
37.95 ± 0.25#a
83.55 ± 0.35a
42.70 ± 0.60#a
155.70 ± 0.70#a
Values are expressed as mean ± SEM. Significantly different from G1 at ;#significantly different from G2 at ;asignificantly different from G3 at <0.05 where, G1 = group 1 (rats given distilled water and feed only), G2 = group 2 (rats induced with phenylhydrazine and left untreated), G3 = group 3 (rats induced with phenylhydrazine and treated with Astymin), G4 = group 4 (rats induced with phenylhydrazine and given low dose of the extract), and G5 = group 5 (rats induced with phenylhydrazine and given high dose of the extract).