Research Article

Haematinic and Hepatoprotective Properties of Telfairia occidentalis Fruit Mesocarp on Phenylhydrazine-Induced Anaemia in Experimental Rats

Table 4

Haematological indices and liver enzymes for the various rat groups at day 3.

Rat groupsRBC (106/L)WBC (109/L)Hb (g/dL)PCV (%)MCV (fL)MCH (pg)MCHC (g/dL)AST (μ/L)ALT (μ/L)ALP (μ/L)

G15.35 ± 1.258.10 ± 0.60#a15.45 ± 0.35#46.30 ± 2.30#85.85 ± 0.65#24.70 ± 0.60#43.55 ± 0.55#51.90 ± 1.60#26.95 ± 0.25#120.00 ± 1.00#
G23.67 ± 0.245.30 ± 0.20a13.05 ± 0.35a40.50 ± 0.5081.25 ± 0.95a33.50 ± 0.40a40.90 ± 0.60a79.70 ± 1.10a40.10 ± 0.40a149.60 ± 1.00a
G33.92 ± 0.3910.80 ± 0.10#15.20 ± 0.70#44.00 ± 1.0085.65 ± 1.05#25.75 ± 0.45#44.00 ± 1.30#50.75 ± 1.35#25.55 ± 1.05#118.50 ± 1.50#
G43.81 ± 0.458.55 ± 0.35#a11.45 ± 0.35#a40.00 ± 1.0079.05 ± 0.85#a33.70 ± 0.10a41.75 ± 0.1582.20 ± 0.40a41.10 ± 0.20a152.80 ± 0.20a
G52.95 ± 0.157.30 ± 0.30#a11.05 ± 0.35#a38.40 ± 0.40a74.75 ± 0.5530.75 ± 0.75#a37.95 ± 0.25#a83.55 ± 0.35a42.70 ± 0.60#a155.70 ± 0.70#a

Values are expressed as mean ± SEM. Significantly different from G1 at ; #significantly different from G2 at ; asignificantly different from G3 at <0.05 where, G1 = group 1 (rats given distilled water and feed only), G2 = group 2 (rats induced with phenylhydrazine and left untreated), G3 = group 3 (rats induced with phenylhydrazine and treated with Astymin), G4 = group 4 (rats induced with phenylhydrazine and given low dose of the extract), and G5 = group 5 (rats induced with phenylhydrazine and given high dose of the extract).