Research Article

Aqueous Extract of Leaves and Flowers of Acmella caulirhiza Reduces the Proliferation of Cancer Cells by Underexpressing Some Genes and Activating Caspase-3

Table 5

Inhibitory concentrations 50 of the AE-Ac on cancer cell lines.

Cell typeCT2ASB-28GL-261B16-F1YUMM 1.7MC-38MCF-7

IC50s24 h>500>500296.81487.94149.42>500>500
48 h>500351.48232.29180.2631.99145.35215.66
72 h114.86

B16-F1: murine melanoma cells; CT2A: nonmetastatic murine glioma (astrocytoma) cells; Gl-261; mouse glioma cells; MC-38: murine colon adenocarcinoma cells; MCF-7: Michigan breast adenocarcinoma cancer foundation cells; SB-28: sleeping beauty mouse glioma cells; YUMM 1.7: Yale University mouse melanoma cells.