Exploring the Impact of Cigarette Smoke Extracts on Vitamin B₁₂: Insights into the Transformation of Methylcobalamin and Hydroxycobalamin to Cyanocobalamin through In Vitro Evaluation

Figure 3

HPLC chromatogram of both control and CSE-treated samples (5 cigarettes); blue: control, red: treated with cigarette smoke extracts: (a) control and treated samples of cyanocobalamin; (b) control and treated samples of methylcobalamin; (c) control and treated samples of hydroxycobalamin; (d) control cyanocobalamin with treated samples of hydroxycobalamin and methylcobalamin; (e) KCN-treated hydroxycobalamin.

(a)

(b)

(c)

(d)

(e)