Research Article

Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection among Kidney Transplant Recipients: A Large Single-Center Experience

Table 1

Baseline characteristics.

CharacteristicsAll (n = 979)Hospitalized (n = 381)Non-hospitalized (n = 598)

Age at transplant (yrs)49.3 ± 13.452.4 ± 13.447.3 ± 13.0<0.001

Age at COVID-19 diagnosis (yrs)56.7 ± 12.959.8 ± 12.953.7 ± 12.6<0.001

Male, %567 (58)238 (63)329 (55)0.02

Non-white, %205 (21)108 (28)97 (16)<0.001

Cause of ESKD, %Diabetes mellitus210 (22)124 (33)86 (14)<0.001
Hypertension114 (12)51 (13)63 (11)
Glomerular disease307 (31)102 (27)205 (34)
Polycystic kidney disease137 (14)35 (9)102 (17)
Other211 (22)69 (18)142 (24)

Living donor, %417 (43)133 (35)284 (48)<0.001

Previous transplant, %201 (21)74 (19)127 (21)0.49

Maintenance immunosuppressive, %Tacrolimus + mycophenolic acid + prednisone615 (63)256 (67)359 (60)0.02
Prednisone based immunosuppression858 (88)347 (91)511 (86)0.009

Vaccinated (%)436 (45)156 (41)280 (47)0.07

Rejection within six months prior to COVID-19 (%)10 (1)4 (1)6 (1)0.94

Baseline serum creatinine before COVID-19 (mg/dl)1.52 ± 0.761.71 ± 0.971.41 ± 0.56<0.001

Baseline eGFR before COVID-19 (mL/min/1.73 m2)53.1 ± 20.947.1 ± 19.857.0 ± 20.8<0.001

Interval from transplant to the first COVID-19 (mo)89.5 ± 85.589.5 ± 85.889.5 ± 85.40.98

Bold values signify statistically significant with p value less than 0.05.