Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection among Kidney Transplant Recipients: A Large Single-Center Experience
Table 1
Baseline characteristics.
Characteristics
All (n = 979)
Hospitalized (n = 381)
Non-hospitalized (n = 598)
Age at transplant (yrs)
49.3 ± 13.4
52.4 ± 13.4
47.3 ± 13.0
<0.001
Age at COVID-19 diagnosis (yrs)
56.7 ± 12.9
59.8 ± 12.9
53.7 ± 12.6
<0.001
Male, %
567 (58)
238 (63)
329 (55)
0.02
Non-white, %
205 (21)
108 (28)
97 (16)
<0.001
Cause of ESKD, %
Diabetes mellitus
210 (22)
124 (33)
86 (14)
<0.001
Hypertension
114 (12)
51 (13)
63 (11)
Glomerular disease
307 (31)
102 (27)
205 (34)
Polycystic kidney disease
137 (14)
35 (9)
102 (17)
Other
211 (22)
69 (18)
142 (24)
Living donor, %
417 (43)
133 (35)
284 (48)
<0.001
Previous transplant, %
201 (21)
74 (19)
127 (21)
0.49
Maintenance immunosuppressive, %
Tacrolimus + mycophenolic acid + prednisone
615 (63)
256 (67)
359 (60)
0.02
Prednisone based immunosuppression
858 (88)
347 (91)
511 (86)
0.009
Vaccinated (%)
436 (45)
156 (41)
280 (47)
0.07
Rejection within six months prior to COVID-19 (%)
10 (1)
4 (1)
6 (1)
0.94
Baseline serum creatinine before COVID-19 (mg/dl)
1.52 ± 0.76
1.71 ± 0.97
1.41 ± 0.56
<0.001
Baseline eGFR before COVID-19 (mL/min/1.73 m2)
53.1 ± 20.9
47.1 ± 19.8
57.0 ± 20.8
<0.001
Interval from transplant to the first COVID-19 (mo)
89.5 ± 85.5
89.5 ± 85.8
89.5 ± 85.4
0.98
Bold values signify statistically significant with p value less than 0.05.