Epidemiology and Performances of Typhidot Immunoassay and Widal Slide Agglutination in the Diagnosis of Typhoid Fever in Febrile Patients in Bafoussam City, Cameroon: A Cross-Sectional Comparative Study

Table 8

Validity of Widal and Typhidot immunoassays as diagnostic tools in comparison with stool culture for the diagnosis of typhoid fever.

Stool culture			value	Sen	Spec	PPV	NPV	Accu	Kappa (95% CI)	Agreement (%)
	Pos	Neg
Typhidot-IgM
Pos	70	47		1	0.823	0.598	1	0.860	0.660	70.26
Neg	0	219	<0.0001	0.948–1.00	0.772–0.867	0.536–0.687	0.983–1.00	0.818–0.895	0.575–0.744
Widal
Pos	69	90		0.985	0.661	0.434	0.994	0.729	0.433	51.54
Neg	1	176	<0.0001	0.923–0.999	0.601–0.718	0.392–0.476	0.961–0.999	0.678–0.776	0.358–0.522

PPV: positive predictive value; NPV: negative predictive value; Pos: positive; Neg: negative; Accu: accuracy; Sen: sensitivity; Spec: specificity; IgM: immunoglobulin M.