Case Report

Paediatric Laryngeal Synovial Sarcoma: Dilemmas and Decision-Making

Table 1

Paediatric cases of laryngeal synovial sarcoma (n = 9).

Author/YearCountry of treatmentAge/SexLaryngeal sitesMaximal diameter (cm)SubtypeManagementFollow-up (years)Status at follow-up

Shein 2021 (Current case)Australia9ML lateral aspect of thyroid cartilage4.0BiphasicWide local excision, selective neck dissection, partial laryngectomy, and + RTX1.0NED
Alhatem 2019USA10MLeft supraglottis, aryepiglottic foldMonophasicEmbolization, I, RTX, and total laryngectomy15Not recorded
Simon 2012UK11MR aryepiglottic foldNot recordedI, DOX, RTX (50.4 Gy), total laryngectomy, and thyroidectomyNED
Fernández-Aceñero 2009Spain12MSupraglotticNot recordedWide local excision and chemotherapy0.33NED
Feng 2017China14ML aryepiglottic fold8BiphasicWide surgical excision, partial laryngectomy, and RTX1.5NED
Morland 1994UK14MArytenoidsBiphasicDebulking, I, ACD, V, RTX (60 Gy), and total laryngectomy0.83NED
Papaspyrou 2003Greece16MAryepiglottic folds and hypopharyngeal walls4BiphasicEndoscopic CO2 laser resection and RTX (50 Gy)2NED
Javed 2015Pakistan16FSupraglottis5Not recordedLateral pharyngectomy, wide local excision, and RTX (60 Gy)2NED
Reddy 2015India17FL supraglottis, arising from L aryepiglottic foldNot recordedEndoscopic resection and RTX (44 Gy)NED

Management listed in order of treatments administered. Left, L; right, R; RTX, radiotherapy; I, Ifosfamide; CIS, cisplatin, CYC, cyclophosphamide, V, vincristine, DOX, doxorubicin; ACD, actinomycin D; docetaxel, DOC; NED, no evidence of disease.