Review Article
Medicine Targeting Epithelial-Mesenchymal Transition to Treat Airway Remodeling and Pulmonary Fibrosis Progression
Table 3
Specific cytokines or amino acids involved in EMT in different respiratory symptoms.
| Compounds | Model | EMT-related target |
| IL-37 [77] | House dust mite-induced asthmatic mice | Erk1/2 and STAT3 | Carbocisteine [78] | OVA-induced asthmatic mice | TGF-β1 | The recombinant pyrin domain protein [79] | Asthmatic mice | TGF-β1/Smad and Jagged1/Notch1 | Empagliflozin [80] | Asthmatic mice | Autophagy |
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