Prevalence of Sleep-Disordered Breathing in Prader–Willi Syndrome
Table 2
PSG data of the patients with PWS (n = 20).
PSG variables
All patients
Sleep efficiency (%)b
83.1 (76.8–88.1)
Sleep latency (minutes)b
12.35 (2.9–48.6)
REM latency (minutes)b
64.5 (55.5–127)
WASO (minutes)b
51.2 (31–80.5)
REM (%) of TSTb
20.85 (17.8–32.7)
AHI (events/hour)b
8.55 (5.8–16.9)
OAHI (events/hour)b
7.29 (1.8–13.5)
CAHI (events/hour)b
1.77 (0.6–4.1)
REM-AHI (events/hour)b
27.8 (15–50.6)
Sleep apnea types, n (%)
CSA
3 (15.0)
OSA
9 (45.0)
Mixed
7 (35.0)
Categories of OSA, n (%)
Mild
3 (15.0)
Moderate
8 (40.0)
Severe
8 (40.0)
Mean sleep SpO2, (%)a
95.45 ± 2.9
SpO2 nadir (%)a
78.6 ± 7.1
% of TST with SPO2 <90% (%)b
0.58 (0.1–2.9)
Peak ETCO2 (mmHg)a
52.0 ± 8.2
Respiratory support, n (%)
7 (35.0)
Data are expressed as mean ± standard deviation or median (IQR). Categorical variables are expressed as frequencies and percentages. WASO, wakefulness after sleep onset; AHI, apnea-hypopnea index; OAHI, obstructive apnea-hypopnea index; CAHI, central apnea-hypopnea index; CSA, central sleep apnea; OSA, obstructive sleep apnea; TST, total sleep time; ETCO2, end-tidal CO2; SpO2, O2 saturation. The table provides descriptive data for the entire population. The bold values represent the median and interquartile range.