Prevalence of Sleep-Disordered Breathing in Prader–Willi Syndrome

Table 3

Regression analysis for AHI and REM-AHI (univariate analysis) with age, BMI, symptoms, GH therapy and AHI, REM-AHI in patients with PWS.

Variables	Logged AHI		Logged REM-AHI
	e^β (95% CI)	value	e^β (95% CI)	value
Age, years	1.01 (0.9, 1.1)	0.680	1.05 (0.9, 1.1)	0.170
Gender (male)	1.41 (0.6, 3.3)	0.415	0.99 (0.4, 2.3)	0.999
BMI (kg/m^2)	1.02 (0.9, 1.0)	0.239	1.03 (1.1, 1.1)	0.031
GH therapy (yes)	1.01 (0.4, 2.5)	0.989	0.98 (0.4, 2.3)	0.952
History of snoring (yes)	1.70 (0.6, 4.9)	0.302	1.97 (0.7, 5.3)	0.161
History of apnea (yes)	1.83 (0.8, 4.2)	0.148	2.06 (1.0, 4.4)	0.063
Reported adenoid/tonsil hypertrophy (yes)	0.75 (0.3, 2.2)	0.576	1.08 (0.4, 3.1)	0.872

BMI, body mass index; GH, hormone therapy. Estimates of effect size are presented as odds ratios and 95% confidence intervals as exponentiated β-coefficients (e^β) for the continuous logged variables for AHI and REM-AHI. Exponentiated β-values indicate the percentage change in the outcome per unit change in the predictor variable.