Potential JAK2 Inhibitors from Selected Natural Compounds: A Promising Approach for Complementary Therapy in Cancer Patients

<div>RMSF for JAK2 backbone atoms complexed with 1ZA, orientin, pulmatin, and chlorogenic acid. Pink and yellow regions demonstrate <i>α</i>-helix and <i>β</i>-strand secondary structures from the RCSB databank. The <i>X</i>-axis illustrates the name and number of residues, while the <i>Y</i>-axis shows the RMSF. JAK2, janus-activated kinase 2; RMSF, root mean square fluctuation.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Potential JAK2 Inhibitors from Selected Natural Compounds: A Promising Approach for Complementary Therapy in Cancer Patients 