Efficacy of the Enteroadsorbent Silicol®gel in Adults with Irritable Bowel Syndrome Subtypes IBS-D or Mixed: Observational Open-Label Study

Table 5

IBS SSS before and after treatment, ITT, and by IBS type.

Study population	IBS severity scoring system (IBS SSS)				Responders (%)
	IBS SSS visit 1; before treatment (baseline)	IBS SSS visit 4; after treatment (4 weeks)	Mean change in; IBS SSS score	value
Overall ()			-163.1		56 (83.6%)
IBS-D ()			-163.5		30 (81.1%)
IBS-M ()			-162.6		27 (90.0%)

IBS = irritable bowel syndrome; IBS-D = with predominant diarrhoea; IBS-M = with mixed bowel habits. Values are supplied as deviation. The mean reduction in IBS SSS after 4 weeks of treatment is significant (). Subjects with a reduction in IBS SSS of >50 from baseline at visit 4 were considered responders. Mean reduction in IBS from severe IBS to mild IBS on Francis et al. scale [35].