Efficacy of the Enteroadsorbent Silicol®gel in Adults with Irritable Bowel Syndrome Subtypes IBS-D or Mixed: Observational Open-Label Study

Table 6

Mean IBS symptoms severity scores: before and after 4 weeks of treatment, total ITT, and by IBS type.

Study population	IBS symptom scores: 0 = not bother me at all, 10 = as bad as I can imagine
		Diarrhoea		Abdominal pain/cramping		Bloating		Flatulence
		Visit 1	Visit 4	Visit 1	Visit 4	Visit 1	Visit 4	Visit 1	Visit 4
Overall; ()
	Change
IBS-D; ()
	Change
IBS-M; ()
	Change

Values are given as deviation. IBS-D = IBS with predominant diarrhoea; IBS-M = IBS with mixed bowel habit. Change = value for difference between visit 1 and visit 4. For all 4 key IBS symptoms, the mean severity scores showed a significant reduction after 4 weeks of treatment. Note. Data is available for telephone visits 2 and 3 (one week and two weeks of treatment, respectively) which shows fast and progressive improvement in all 4 symptoms across the duration of the study.