Exploiting of Green Synthesized Metal Oxide Nanoparticles in the Potentiometric Determination of Metformin Hydrochloride in Pharmaceutical Products

Table 6

The results of the MTF determination in its dosage forms using MTF-PT, MTF-PT-Al₂O₃NP-modified, and MTF-PT-NiONP-modified sensors with respect to the previously reported results.

	MTF-PT conventional electrode			MTF-PT-Al2O3NP-; modified electrode			MTF-PT-NiONP-; modified electrode			Reference method [59]
	Test sample	Found	% recovery	Test sample	Found	% recovery	Test sample	Found	%Recovery
Statistical analysis	6	5.98	99.66	10	10.00	100.00	10	9.96	99.60
	5	4.97	99.40	8	7.96	99.75	8	7.94	99.25
	4.3	4.25	98.83	6	5.94	99.00	6	5.96	99.33
	4	3.98	99.50	4	4.00	100.00	4	3.93	98.25
	3	2.98	99.33	3	2.99	99.67	3	2.99	99.67
	2	1.96	98.00	2	1.98	99.00	2	2.00	100.00
Mean ± SD	99.12 ± 0.62			99.57 ± 0.46			99.35 ± 0.60			99.25 ± 0.72
n	6			6			6			6
Variance	0.38			0.21			0.36			0.52
%SE	0.25			0.19			0.24			0.29
%RSD	0.63			0.46			0.60			0.74
t-test	0.337 (2.228)			0.922 (2.228)			0.266 (2.228)
F-test	1.37 (5.05)			2.48 (5.05)			1.44 (5.05)

^∗The tabulated values of “t-test” and “F-test” at confidence level p = 0.05.