Identification of ZIC2 as a Potential Biomarker Linked with the Clinical Progression and Immune Infiltration of Oral Cancer: A Multicenter Study

<div>The effect of knocking down ZIC2 expression on biological functions of Cal-27 cells: (a) expression of ZIC2 mRNA between Cal-27 cells transfected with negative control (NC) RNA and ZIC2 siRNA; (b) box plot of OD values from CCK8 assay; (c) images of cell migration around scratches; (d) box plot of wound healing percentage at 48 h; (e) images of cells passing through the basement membrane of Transwell chambers; (f) box plot of number of invaded cells at 48 h. <span class="nowrap"><svg height="10.7395pt" id="M56" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 56.4993 10.7395" width="56.4993pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 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International Journal of Genomics

fig14

Figure 14

Figure 14: Identification of ZIC2 as a Potential Biomarker Linked with the Clinical Progression and Immune Infiltration of Oral Cancer: A Multicenter Study 

Figure 14 | Identification of ZIC2 as a Potential Biomarker Linked with the Clinical Progression and Immune Infiltration of Oral Cancer: A Multicenter Study 