Liver Segment Disposition of Hepatocellular Carcinoma Predicts Microvascular Invasion

Table 2

Findings by microvascular invasion.

Characteristics	Microvascular invasion	p-value
Median number of affected segments	2.0 vs. 1.0	0.01
Median number of HCCs	1.0 vs. 1.0	0.23
Median HCC tumor size	3.5 vs. 2.5	0.09
Median AFP	18.8 vs. 8.8	0.02
HCC etiology, %
HCV	22.0 vs. 26.3	0.60
HBV	60.0 vs. 21.7	0.08
Alcohol	13.3 vs. 24.8	0.52
NAFLD	36.4 vs. 22.0	0.28
Segment
Segment 1	0.0 vs. 23.5	1.00
Segment 2	35.3 vs. 21.4	0.22
Segment 3	26.3 vs. 22.8	0.77
Segment 4a	36.8 vs. 20.8	0.14
Segment 4b	35.7 vs. 21.7	0.31
Segment 5	34.5 vs. 19.8	0.10
Segment 6	25.6 vs. 22.2	0.68
Segment 7	23.8 vs. 23.1	0.93
Segment 8	25.6 vs. 22.1	0.66
Segment 2 and 3	71.4 vs. 20.4	0.01
Segment 4a and b	34.6 vs. 20.2	0.12
Segment 5 and 6	26.9 vs. 20.6	0.42
Segment 6 and 7	24.2 vs. 22.4	0.82
Segment 7 and 8	24.2 vs. 22.2	0.79
Segment 4b and 5	37.5 vs. 16.3	0.01
Segment 4a and 8	27.3 vs. 20.0	0.35
Segment 4b and 8	29.1 vs. 18.5	0.17
Segment 5 and 8	42.9 vs. 20.8	0.09
BCLC A, B, and C stages	18.5 vs. 36.0 vs. 66.7	0.04
HCC pathology stage, 1, 2, and 3	12.4 vs. 51.6 vs. 50.0	≤0.01
HCC recurrence	78.6 vs. 14.0	≤0.01
Median survival, months	50 vs. 137	0.01

HCC: hepatocellular carcinoma, AFP: alpha fetoprotein, HCV: hepatitis C virus, HBV: hepatitis B virus, NAFLD: Nonalcoholic fatty liver disease, BCLC: Barcelona Clinic Liver Cancer, , .