Research Article
Full-Length Genome Sequencing and Analysis of Hepatitis B Viruses Isolated from Iraqi Patients
Table 4
Mutations and amino acid substitutions in the X region.
| Region | Mutation | aa substitution | Mutation possible effect | Reference |
| X (1374–1838 nt) | T1449C | C26R | CHB, LC | [27] | T1464C | S31P | CHB, LC | [27] | T1470C | S33P | U | Current study | A1479T | T36S | LC | [28] | T1494A | S41T | U | Current study | C1509T | P46S | CHB, LC | [27] | A1634C | Q87H | U | Current study | A1637C | I88F | U | Current study | C1653T | H94Y | CHB, HCC | [27] | C1678T | A102V | CHB, LC | [27] | A1752C | I127L | CHB, LC | [27] | A1762T | K130M | CHB, LC | [27] | T1768A | F132Y | LC | [28] |
|
|
Bold font mutation: indicated known referenced mutation, aa: amino acid, CHB: chronic hepatitis, HCC: hepatocellular carcinoma, LC: liver cirrhosis, U: uncharacterized effect.
|