Prognostic Impact of Tumor Budding on Moroccan Colon Cancer Patients

Table 5

Association between tumor budding and clinicopathological features.

Variables	Low-grade tumor budding	High-grade tumor budding	value
Age			0.03
<57	36 (60.0%)	17 (42.5%)
≥57	24 (40.0%)	23 (57.5%)
Genre			0.2
Female	28 (46.7%)	15 (37.5%)
Male	32 (53.3%)	25 (62.5%)
Tumor site			0.4
Right colon	22 (36.7%)	16 (40.0%)
Left colon	38 (63.3%)	24 (60.0%)
Histologic subtype			0.2
Adenocarcinoma	54 (90.0%)	32 (80.0%)
Mucinous	3 (5.0%)	6 (15.0%)
Others	3 (5.0%)	2 (5.0%)
Histologic grade			0.5
Well	28 (46.7%)	18 (45.0%)
Moderate	26 (43.3%)	20 (50.0%)
Poor	6 (10.0%)	2 (5.0%)
Venous invasion			0.05
Presence	9 (15.3%)	11 (28.2%)
Absence	50 (84.7%)	28 (71.8%)
Perineural invasion			0.02
Presence	5 (8.5%)	10 (25.6%)
Absence	54 (91.5%)	29 (74.4%)
Number of removed lymph nodes
Mean (SD)	21.7 (±8.5)	19.2 (±6.9)	0.2
˂12	5 (8.6%)	7 (17.9%)	0.1
˃12	53 (91.4%)	32 (82.1%)
Positive lymph node
Mean (SD)	1.2 (±0.0)	1.4 (±2.9)	0.8
Presence	19 (32.2%)	13 (33.3%)	0.5
Absence	40 (67.8%)	26 (66.7%)
RGL
Mean (SD)	0.06 (±0.03)	0.063 (±0.2)	0.9
Synchronous metastasis (M)			˂0.001
M0	57 (95.0%)	26 (66.7%)
M1	3 (5.0%)	13 (33.3%)
Disease stages			0.001
I	2 (3.3%)	2 ((5.0%)
II	37 (61.7%)	15 (37.5%)
III	18 (30.0%)	9 (22.5%)
IV	3 (5.0%)	14 (35.0%)
Follow-up time (months)	27.0 (±19.3)	24.8 (±13.3)	0.7
Recurrence
(+)	14 (23.3%)	15 (38.5%)	0.04
(−)	46 (76.7%)	24 (61.5%)
Recurrence patterns
Liver	2 (14.3%)	3 (20%)	0.07
Lung	3 (21.4%)	3 (20%)
Peritoneum	2 (14.3%)	5 (33.3%)
Local recurrence	6 (42.9%)	3 (20%)
Others	1 (7.1%)	1 (6.7%)
Mortality			0.02
Death cases	7 (11.7%)	11 (28.2%)
Censored cases	53 (88.3%)	28 (71.8%)