Segmental Arterial Mediolysis: A Multiguised Vasospastic Arteriopathy with Collateral Mesangial Cell Hyperplasia and Cardiac Toxicity Generated by Norepinephrine and Hyperdense Adrenoceptors Alone or by Crosstalk with Other Pressor Agents

Figure 15

Segmental arterial mediolysis reparative phase. Early reparative phase. The black arrow points to a florid proliferation of young granulation tissue developing in the tear space between the outer media and adventitia. Bleeding from injured capillaries has initiated hematoma formation. The white arrow points to a beginning dissection between the outer media and adventitia. Hematoxylin & eosin ×15 (adapted with permission from the International Journal of Surgical Pathology 15(2) copyright 2007, Sage Publications, Inc.).