Research Article
Development and Validation of Analytical Procedure for Elemental Impurities in Rosuvastatin Calcium Tablets by ICP-MS and Microwave Digestion
| | Parameters | Setup |
| | Nebulization temperature (°C) | 2.7 | | Peristaltic pump speed (r·min−1) | 40 | | Nebulizer gas flow rate (L·min−1) | 0.9964 | | Cooling gas flow rate (L·min−1) | 14 | | Auxiliary gas flow rate (L·min−1) | 0.8 | | Sampling depth (mm) | 5 | | Collision gas flow rate (mL·min−1) | 5.4 | | Plasma power | 1550 | | CCT focus lens | 3.6 | | Scan mode | KED | | Number of scans | 20 | | Time per scan (s) | 0.5 | | Time of dwell (s) | 0.05 | | Time of uptake (s) | 45 | | Time of wash (s) | 30 | | Torch vertical position | 0.77 | | Extraction lens 2 | −200.7 |
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