Comparing the Efficacy of Two Cognitive Screening Tools in Identifying Gray and White Matter Brain Damage among Older Adults

Table 3

Brain magnetic resonance imaging volumetric quantification of older adults (N = 90) with no cognitive impairment (NCI), mild cognitive impairment (MCI), or moderate cognitive impairment (MoCI).

Brain tissue-specific and region-specific abnormalities	NCI (n = 39)	MCI (n = 36)	MoCI (n = 15)	P value
	Mean ± SD	Mean ± SD	Mean ± SD
Periventricular white matter (cm^3)	1.05 ± 0.83	1.28 ± 0.91	1.40 ± 0.99	0.350
Deep white matter (cm^3)	1.08 ± 0.87	1.17 ± 0.91	1.33 ± 1.05	0.653
Parietal atrophy (cm^3)	0.77 ± 0.74	0.69 ± 0.67	1.07 ± 0.70	0.230
Medial temporal lobe atrophy (cm^3)	0.62 ± 0.75^A	0.72 ± 0.74^A	1.73 ± 1.03^B	<0.001
Global cortical atrophy (cm^3)	0.85 ± 0.81	0.92 ± 0.84	1.07 ± 0.70	0.668

Indicate statistically significant values. Means ± standard deviation (SD) with different letters represents statistically significant values () in the comparison between groups according to the Tukey’s post hoc test.