Comparing the Efficacy of Two Cognitive Screening Tools in Identifying Gray and White Matter Brain Damage among Older Adults

Table 4

Brain magnetic resonance imaging volumetric quantification of older adults (N = 90) with no cognitive impairment (NCI), mild cognitive impairment (MCI), or moderate cognitive impairment (MoCI) also screened by the Mini-Mental State Examination (MMSE).

Brain tissue-specific and region-specific abnormalities	NCI (n = 53)	MCI (n = 31)	MoCI (n = 6)	P value
	Mean ± SD	Mean ± SD	Mean ± SD
Periventricular white matter (cm^3)	1.23 ± 0.82	1.13 ± 0.99	1.33 ± 1.03	0.831
Deep white matter (cm^3)	1.21 ± 0.89	1.03 ± 0.95	1.33 ± 1.03	0.621
Parietal atrophy (cm^3)	0.77 ± 0.70	0.74 ± 0.77	1.17 ± 0.41	0.400
Medial temporal lobe atrophy (cm^3)	0.58 ± 0.75^A	1.13 ± 0.96^B	1.67 ± 0.82^B	0.001
Global cortical atrophy (cm^3)	0.91 ± 0.82	0.90 ± 0.83	1.00 ± 0.63	0.962

Indicate statistically significant values. Means ± standard deviation (SD) with different letters represents statistically significant values () in the comparison between groups according to the Tukey’s post hoc test.