Research Article
A Retrospective Observational Study on Disease Characteristics and Treatment Patterns of Giant Cell Tumor of the Bone in China
Table 2
Disease characteristics (FAS and UMNAS).
| | Item | Description | FAS () | UMNAS () | | Primary diagnosis () | Last disease recurrence () | Primary diagnosis () | Last disease recurrence () |
| | Target lesion anatomic site, (%) | Extremities | | | | | | Upper limbs | 116 (17.4) | 40 (20.0) | 24 (13.9) | 12 (15.0) | | Lower limbs | 462 (69.2) | 149 (74.5) | 78 (45.1) | 59 (73.8) | | Axial bone | | | | | | Spine | 55 (8.2) | 7 (3.5) | 55 (31.8) | 7 (8.8) | | Pelvis | 34 (5.1) | 4 (2.0) | 15 (8.7) | 2 (2.5) |
| | Metastasis, (%) | Yes | 12 (1.8) | 16 (8.0) | 12 (6.9) | 16 (20.0) | | No | 656 (98.2) | 184 (92.0) | 161 (93.1) | 64 (80.0) |
| | Spine or sacrum GCTB or metastatic GCTB, (%) | Yes | 66 (9.9) | 23 (11.5) | 66 (38.2) | 23 (28.8) | | No | 602 (90.1) | 177 (88.5) | 107 (61.9) | 57 (71.3) |
| | Pathological diagnosis, (%) | BGCT | 668 (100.0) | 200 (100.0) | 173 (100.0) | 80 (100.0) |
| | Secondary malignancy diagnosis | MGCT | | 1 (0.50) | | | | Malignant mesenchymal tumor | | 1 (0.50) | | 1 (12.5) | | Undifferentiated small cell sarcoma | | 1 (0.50) | | 1 (12.5) |
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BGCT = benign giant cell tumor; FAS = full analysis set; GCTB = giant cell tumor of the bone; MGCT = malignant giant cell tumor; UMNAS = unmet medical needs analysis set.
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