Physiopathology and Treatment of Obesity and Overweight: A Proposal for a New Anorectic

Table 1

Main advantages and disadvantages of caloric restriction and fasting dietary approaches for obesity.

Dietary regimen	Advantages	Disadvantages
Caloric restriction	(i) Low risk of macronutrients deficit; (ii) Long-term effect; (iii) Possibility to graduate restriction	(i) No measure to check compliance; (ii) Long time needed for effect; (iii) Need for intensive patient engagement
Intermittent fasting	(i) Low risk of macronutrients deficit; (ii) Fast effect; (iii) No need for laboratory monitoring	(i) Interindividual variability; (ii) Lack of measures for compliance control; (iii) Risk of dehydration; (iv) Sustained effect lacking