Research Article
The Pattern of Microorganisms and Drug Susceptibility in Pediatric Oncologic Patients with Febrile Neutropenia
Table 7
Therapeutic response in febrile neutropenic children with Gram-negative bacterial infection.
| Characteristics | Non-antibiotics-resistant bacterial infection (N = 84) | Antibiotics-resistant bacterial infection (N = 20) | value+ |
| Fever days after empirical antibiotic therapy (median, range) | 7 (1, 36) | 15 (8, 23) | 0.001 | Clinical outcome | 24 (28.6%) | 10 (50%) | 0.109 | Oxygen therapy | 22 (26.2%) | 9 (45%) | 0.11 | Shock | 21 (25%) | 8 (40%) | 0.266 | Admission to the intensive care unit | 12 (14.3%) | 7 (35%) | 0.05 | Renal dysfunction | 3 (3.6%) | 4 (20%) | 0.024 | Hepatic dysfunction | 8 (9.5%) | 1 (5%) | 0.477 | Mechanical ventilator care | 2 (2.4%) | 5 (25%) | 0.124 | Duration of hospitalization (median, range) | 29 (1, 150) | 31 (7, 43) | 0.790 | Overall 2-week mortality | 3 (3.6%) | 4 (20%) | 0.024 |
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value calculated by the Mann–Whitney test or Fisher’s exact test as appropriate. |