Bisphenol-A Abrogates Proliferation and Differentiation of C2C12 Mouse Myoblasts via Downregulation of Phospho-P65 NF-κB Signaling Pathway

Figure 1

BPA inhibited C2C12 myoblast cell proliferation. C2C12 myoblast cells were cultured in a growth medium in the absence or presence of BPA at the indicated concentrations for 24, 48, and 72 h. Photomicrographs of cell morphology before and after BPA treatments (a). Cell viability was assessed by MTT assay (b) and cell counting (c). Arrowheads indicate cytoplasmic extension; n s.: not significant; ; ; compared to the control group. Scale bar = 200 µm.

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