Research Article
White Matter Microstructural Alterations over the Year after Acute Ischemic Stroke in Patients with Baseline Impaired Cognitive Functions
Table 1
Clinical characteristics of the AIS and HC groups.
| | Variables | HC group
(n = 25) | AIS group (baseline)
(n = 60) | P |
| | Demographic characteristics | | | | | Gender (male), n | 16 | 42 | 0.588 | | Age (year), mean (SD) | 56.16 (6.96) | 57.70 (7.33) | 0.337 | | Education (year), mean (SD) | 12.56 (3.22) | 11.23 (3.90) | 0.080 | | Vascular risk factors | | | | | Body mass index, mean (SD) | 24.79 (2.83) | 25.60 (2.71) | 0.183 | | Hypertension, n | 13 | 49 | 0.008 | | Hyperlipemia, n | 9 | 34 | 0.082 | | Diabetes, n | 5 | 16 | 0.516 | | History of smoking, n | 10 | 43 | 0.006 | | Cognitive scores | | | | | MMSE score, mean (SD) | 28.80 (1.11) | 21.83 (5.15) | <0.001 | | MoCA score, mean (SD) | 27.36 (1.38) | 17.71 (4.92) | <0.001 | | Radiological data | | | | | WMH scale, median (IQR) | 2 (2–2.5) | 2 (2–3) | 0.054 | | PVH scale, median (IQR) | 1 (1–1.5) | 1 (1–2) | 0.086 | | DWMH scale, median (IQR) | 1 (1) | 1 (1) | 0.025 | | MTA score, median (IQR) | 0 (0–0.5) | 0 (0–0.5) | – |
|
|
Abbreviations: MMSE, mini-mental state examination; MoCA, Montreal Cognitive Assessment; WMH, white matter hyperintensity; PVH, periventricular hyperintensity; DWMH, deep white matter hyperintensity; MTA, medial temporal lobe atrophy; SD, standard deviation; IQR, interquartile range.
|
