Research Article

Serum Level of Brain-Derived Neurotrophic Factor and Thrombotic Type Are Predictive of Cognitive Impairment in the Acute Period of Ischemic Strokes Patients

Table 1

Demographic and clinical characteristics of studied population.

DemographicsGroups value
Group 1 (n = 59)Group 2 (n = 30)

Age, M ± SD61.19 ± 9.6157.84 ± 4.89
Sex, abs. (%)
 M37 (62.7%)21 (70.0%)χ2 = 0.46 df = 2
 F22 (37.3%)9 (30.0%)
Clinical type of stroke abs. (%)
 Thrombotic45 (76.3%)
 Embolic14 (23.7%)
NIHSS, M ± SD
 1st day7.02 ± 3.88
 14th day4.42 ± 3.39
value0.038
BDNF level (pg/ml), M ± SD
 1st day307.87 ± 245.44734.65 ± 417.53
 14th day470.94 ± 376.17
value0.503
Cognitive impairment abs. (%)
 1st day32 (54.2%)7 (23.3%)χ2 = 7.12, df = 1,
 14th day28 (47.6%)
valueMac–Nemar’s χ2 = 0.624, df = 1,