|
| Author and year | Study title | Web link/doi | Comments | Focus of the study | Test intervention reported efficiency in SSTI resolution |
|
| Winstead, 2012 [71] | Evaluating and Managing Uncomplicated Skin and Soft Tissue Infections Associated with Community-Associated Methicillin-Resistant Staphylococcus aureus for Outpatients: A Review of the Literature | https://doi.org/10.1891/1939-2095.5.2.98 | For final inclusion | Traditional I&D | Not Documented |
|
| Llera et al., 1984 [68] | Cutaneous Abscesses: Natural History and Management in an Outpatient Facility | https://doi.org/10.1016/0736-4679(84)90002-7 | For final inclusion | Traditional I&D | 73% |
|
| Singer and Talan, 2014 [72] | Management of Skin Abscesses in the Era of Methicillin-Resistant Staphylococcus aureus | https://doi.org/10.1056/NEJMra1212788 | For final inclusion | Traditional I&D | 80% |
|
| Alder et al.,, 2011 [64] | A comparison of Traditional Incision and Drainage versus Catheter Drainage of Soft Tissue Abscesses in Children | https://doi.org/10.1016/j.jpedsurg.2011.05.025 | For final inclusion | Catheter drainage | 75% |
|
| Mahida et al. 2015 [74] | Using Quality Improvement Methods to Change Surgical Practice: A Case Example of Pediatric Soft Tissue Abscesses | https://doi.org/10.1097/QMH.0000000000000054 | For final inclusion | Catheter drainage | 75% |
|
| Yang et al., 2017 [33] | A High-Vacuum Wound Drainage System Reduces Pain and Length of Treatment for Pediatric Soft Tissue Abscesses | https://doi.org/10.1007/s00431-016-2835-2 | For final inclusion | Suction drainage | 96% |
|
| Zihmin et al. 2020 [77] | Therapeutic effect of Topical Negative Pressure Therapy/Vacuum-Associated Closure Therapy on Cephalic Facial Skin Abscess | https://doi.org/10.1089/sur.2019.184 | For final inclusion | Suction drainage | 10–12 days |
|
| Tsoraides et al., 2010 [70] | Incision and Loop Drainage: A Minimally Invasive Technique for Subcutaneouse Abscess Management in Children | https://doi.org/10.1016/j.jpedsurg.2009.06.013 | For final inclusion | Loop drainage | 94.50% |
|
| Schechter-Perkins, 2020 [21] | Loop Drainage Is Noninferior to Traditional Incision and Drainage of Cutaneous Abscesses in the Emergency Department | https://doi.org/10.1111/acem.13981 | For final inclusion | Loop drainage | 88% |
|
| Ozturan et al., 2009 [75] | Comparison of Loop and Primary Incision and Drainage Techniques in the Emergency Department | https://doi.org/10.1016/j.ajem.2017.01.036 | For final inclusion | Loop drainage | 87% |
|
| McNamara et al., 2011 [65] | An Alternative to Open Incision and Drainage for Community-Acquired Soft Tissue Abscesses in Children | https://doi.org/10.1016/j.jpedsurg.2010.08.019 | For final inclusion | Loop drainage | 100% |
|
| Gottlieb et al., 2021 [57] | Comparison of the Loop Technique with Incision and Drainage for Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis | https://doi.org/10.1111/acem.14151 | For final inclusion | Loop drainage | 91.73% |
|
| Ladde et al., 2015 [73] | The Loop Technique: A Novel Incision and Drainage Technique in the Treatment of Skin Abscesses in a Pediatric ED | https://doi.org/10.1016/j.ajem.2014.10.014 | For final inclusion | Loop drainage | 98.60% |
|
| Long and Apiril, 2019 [76] | Is Loop Drainage Technique More Effective for Treatment of Soft Tissue Abscess Compared with Conventional Incision and Drainage? | https://doi.org/10.1016/j.annemergmed.2018.02.006 | For final inclusion | Loop drainage | 95.9% |
|
| Rencher et al., 2016 [66] | Comparison of Loop Drainage versus Incision and Drainage for Abscesses in Children | https://doi.org/10.1097/PEC.0000000000001732 | For final inclusion | Loop drainage | 92.7% |
|
| Eryilmaz et al., 2005 [69] | Management of Lactational Breast Abscesses | https://doi.org/10.1016/j.breast.2004.12.001 | For final inclusion | Needle aspiration | 41% |
|
| Gaspari et al., 2011 [19] | A Randomised Controlled Trial of Incision and Drainage versus Ultrasonographically Guided Needle Aspiration for Skin Abscesses and the Effect of Methicillin-Resistant Staphylococcus aureus | https://doi.org/10.1016/j.annemergmed.2010.11.021 | For final inclusion | Needle aspiration | 26% |
|
| Lasithiotakis et al., 2018 [32] | Aspiration for Acute Pilonidal Abscess: A Cohort Study | https://doi.org/10.1016/j.jss.2017.09.051 | For final inclusion | Needle aspiration | 83% |
|
| Singer et al., 2011 [67] | Primary Closure of Cutaneous Abscesses: A Systematic Review | https://doi.org/10.1016/j.ajem.2009.10.004 | For final inclusion | I&D with primary closure | 92.4% |
|
| Kotlářová et al., 2021 [42] | Antibiotic Therapy in the Treatment of Skin Abscess Meta-Analysis | https://doi.org/10.33699/PIS.2021.100.7.325-329 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Talan, 2016 [15] | Trimethoprim-Sulfamethoxazole versus Placebo for Uncomplicated Skin Abscess | https://doi.org/10.1056/NEJMoa1507476 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Daum et al., 2017 [14] | A Placebo-Controlled Trial of Antibiotics for Smaller Skin Abscesses | https://doi.org/10.1056/NEJMoa1607033 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Duong et al., 2010 [37] | Randomised, Controlled Trial of Antibiotics in the Management of Community-Acquired Skin Abscesses in the Pediatric Patient | https://doi.org/10.1016/j.annemergmed.2009.03.014 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Cenizal et al., 2007 [35] | Trimethoprim-Sulfamethoxazole or Doxycycline for Skin and Soft Tissue Infections | https://doi.org/10.1128/aac.00206-07 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Daum et al. 2016 [36] | Clindamycin versus Trimethoprim-Sulfamethoxazole versus Placebo for Uncomplicated Skin and Soft Tissue Abscesses | https://doi.org/10.1093/ofid/ofw194.111 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Elliott et al., 2009 [38] | Empiric Antimicrobial Therapy for Pediatric Skin and Soft Tissue Infections in the Era of Methicillin-Resistant Staphylococcus aureus | https://doi.org/10.1542/peds.2008-2428 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Gottlieb, 2017 [40] | Comparison of Trimethoprim-Sulfamethoxazole Versus Placebo for Uncomplicated Skin Abscesses | https://doi.org/10.1017/cem.2016.367 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Lee et al., 2004 [43] | Management and Outcome of Children with Skin and Soft Tissue Abscesses Caused by Community-Acquired Methicillin-Resistant Staphylococcus aureus | https://doi.org/10.1097/01.inf.0000109288.06912.21 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| López et al., 2018 [44] | Comparative Study of Drainage and Antibiotics versus Drainage Only in the Management of Primary Subcutaneous Abscesses | https://doi.org/10.1089/sur.2017.225 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Powers, 1991 [46] | Soft Tissue Infections in the Emergency Department: The Case for the Use of 'Simple' Antibiotics | https://doi.org/10.1097/00007611-199111000-00005 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Talan,, 2018 [47] | Subgroup Analysis of Antibiotic Treatment for Skin Abscesses | https://doi.org/10.1016/j.annemergmed.2017.07.483 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Vermandere et al., 2018 [48] | Antibiotics after Incision and Drainage for Uncomplicated Skin Abscesses: A Clinical Practice Guideline | https://doi.org/10.1136/bmj.k243 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Fahimi et al., 2015 [39] | The Role of Adjunctive Antibiotics in the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis | https://doi.org/10.1017/cem.2014.52 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Gottlieb, 2019 [41] | Systemic Antibiotics for the Treatment of Skin and Soft Tissue Abscesses: A Systematic Review and Meta-Analysis | https://doi.org/10.1016/j.annemergmed.2018.02.011 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Mistry et al., 2014 [45] | Clinical Management of Skin and Soft Tissue Infections in the U.S. Emergency Departments | https://doi.org/10.5811/westjem.2014.4.20583 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Schmitz et al., 2010 [20] | Randomised Controlled Trial of Trimethoprim-Sulfamethoxazole for Uncomplicated Skin Abscesses in Patients at Risk for Community-Associated Methicillin-Resistant Staphylococcus aureus Infection | https://doi.org/10.1016/j.annemergmed.2010.03.002 | Excluded: the effects of antibiotics following traditional I&D | | N/A |
|
| Uknown | Outcomes of a Novel Technique of Mini- Incision and Self-Express (Mise) for Breast Abscess | https://beta.clinicaltrials.gov/study/NCT05762016 | Excluded: this is a protocol | | N/A |
|
| Gulack, 2023 [54] | Conservative Management of Cutaneous Abscess | https://beta.clinicaltrials.gov/study/NCT05461053 | Excluded: this is a protocol | | N/A |
|
| Miller, 2023 [53] | Short- and Long-Term Outcomes of Doxycycline versus Trimethoprim-Sulfamethoxazole for Skin and Soft Tissue Infections Treatment | https://clinicaltrials.gov/show/NCT03637400 | Excluded: this is a protocol | | N/A |
|
| Koehler and Nakayama, 2009 [49] | Treatment of Cutaneous Abscesses without Postoperative Dressing Changes | https://doi.org/10.1016/j.aorn.2009.04.026 | Excluded: I&D with or without packing | | N/A |
|
| Washington University School of Medicine [80] | Abscess Packing versus Wick Placement after Incision and Drainage | https://clinicaltrials.gov/show/NCT01281930 | Excluded: I&D with or without packing | | N/A |
|
| O'Malley et al., 2009 [50] | Routine Packing of Simple Cutaneous Abscesses is Painful and Probably Unnecessary | https://doi.org/10.1111/j.1553-2712.2009.00409.x | Excluded: I&D with/without packing | | N/A |
|
| Oehme et al., 2020 [3] | Simple Wound Irrigation in the Postoperative Treatment for Surgically Drained Spontaneous Soft Tissue Abscesses: A Prospective, Randomised Controlled Trial | https://doi.org/10.1007/s00268-020-05738-1 | Excluded: wound irrigation not intervention | | N/A |
|
| Rühle, 2021 [55] | International Survey Evaluating Treatment of Primary Superficial Skin Abscesses | https://doi.org/10.1007/s00068-019-01279-y | Excluded: no study of intervention and survey of surgeons | | N/A |
|
| Brody et al. 2019 [59] | A Novel Silicon Device for the Packing of Cutaneous Abscesses | https://doi.org/10.1016/j.jemermed.2018.12.009 | Excluded: serious conflicts of interest | | N/A |
|
| Gottlieb and Peksa,, 2018 [56] | Comparison of the Loop Technique with Incision and Drainage for Soft Tissue Abscesses: A Systematic Review and Meta-Analysis | https://doi.org/10.1016/j.ajem.2017.09.007 | Excluded: older version of updated study | | N/A |
|
| Long and Gottlieb, 2022 [58] | Diagnosis and Management of Cellulitis and Abscess in the Emergency Department Setting: An Evidence-Based Review | https://doi.org/10.1016/j.jemermed.2021.09.015 | Excluded: Not specific to type II SSTIs | | N/A |
|
