Review Article
The Molecular Blueprint for Chronic Obstructive Pulmonary Disease (COPD): A New Paradigm for Diagnosis and Therapeutics
| S. no. | Inhibitor/drug | Mechanism/effect | Clinical progress | References |
| 1 | Eleuquin (EL246) | Cell adhesion inhibitor | Under predevelopment by LigoCyte | [185] |
| 2 | BIBW 2948 | EGFR internalization reducer | 4 Weeks treatment (NCT00423137) | [186] |
| 3 | Bosentan | Endothelin receptor inhibitor | 18 Months treatment (NCT02093195) | [187, 188] |
| 4 | Solithromycin | Macrolide antibiotic | Early termination of the trial (NCT02628769) | [189] |
| 5 | Thiazolidinediones | PPARγ agonists | 10 Months treatment (NCT00103922) | [190, 191] |
|
|