Research Article

Complications during Adolescence Predict Mortality in Young Adults with Childhood Onset Type 1 Diabetes

Table 1

Characteristics at final visit for cohort, alive, and deceased.

AllAliveDeceasedp^

n40939514
Male196 (48)188 (48)8 (57)0.48
Age (years)17.4 (16.0–18.9)17.4 (16.0–18.9)17.5 (16.4–18.7)0.85
Duration (years)9.3 (5.9–12.3)9.3 (6.0–12.3)6.9 (5.3–12.1)0.34
HbA1c8.8 (7.8–10.0)8.8 (7.7–10.0)8.7 (7.9–9.4)0.76
SBP-SDS0.43 (0.0–0.92)0.46 (0.0–0.9)0.01 (−0.8–0.5)0.07
DBP-SDS0.77 (0.33–1.4)0.77 (0.34–1.4)0.6 (0.1–1.2)0.32
BMI-SDS0.59 (0.1–1.0)0.61 (0.1–1.1)0.4 (0.1–0.9)0.53
Retinopathy176/388 (45)173/377 (46)3/11 (27)0.22
Elevated AER115/291 (40)18/375 (5)5/10 (50)0.50
Microalbuminuria23/277 (8)23/268 (9)0/90.36
Peripheral neuropathy62/393 (16)58/380 (15)4/13 (31)0.13
Cardiac autonomic neuropathy79/391 (20)73/378 (19)6/13 (46)0.02
Abnormal pupillary response70/232 (30)67/224 (30)3/8 (38)0.65
Resting pupillary diameter < 4.77 mm22/232 (10)20/224 (9)2/8 (25)0.13

Data are n (%) or median (IQR). #Urine sample not available for four of deceased group at last visit. ^Comparing deceased vs. alive.