Peptide Helix-Y¹² as Potential Effector for Peroxisome Proliferator-Activated Receptors

Figure 4

Structure-based sequence alignment of the three PPAR variants. Top to bottom: PPARγ (PDBID 4y29) versus PPARα (PDBID 3et1), PPARγ (PDBID 4y29) versus PPARβ/δ (PDBID 3gz9), and PPARα (PDBID 3et1) versus PPARβ/δ (PDBID 3gz9). For each pair of variants, aligned length, RMSD, TM-score, and sequence identity were reported using the TM-align algorithm. For each aligned residue pair, “:” denotes distance <5 : 0 Å, “.” denotes farther aligned residues, and “*” denotes identical residues.