Research Article
The Causal Relationship between Angina Pectoris and Gout Based on Two Sample Mendelian Randomization
Table 3
Status of instrumental variables related to blood uric acid levels.
| SNP | Position | chr | EA | OA | eaf.exposure | beta.exposure | se.exposure | value exposure | F |
| rs11202346 | 88908912 | 10 | T | G | 0.2224 | 0.03489 | 0.00528 | 3.89E − 11 | 43.66506327 | rs11227230 | 65356674 | 11 | A | G | 0.0778 | −0.1816 | 0.007896 | 4.92E − 117 | 528.9533952 | rs11231334 | 62844587 | 11 | C | T | 0.2757 | −0.04296 | 0.005456 | 3.46E − 15 | 61.99830583 | rs11231890 | 64611543 | 11 | T | C | 0.5324 | −0.07209 | 0.004412 | 5.14E − 60 | 266.9801935 | rs1165196 | 25813150 | 6 | A | G | 0.8407 | 0.05158 | 0.0057 | 1.43E − 19 | 81.88662358 | rs12051440 | 80163600 | 16 | T | C | 0.9069 | −0.04116 | 0.007224 | 1.21E − 08 | 32.46349378 | rs1260326 | 27730940 | 2 | C | T | 0.4409 | −0.03472 | 0.00424 | 2.65E − 16 | 67.05446778 | rs1549287 | 69590366 | 16 | G | A | 0.8452 | −0.03315 | 0.005792 | 1.05E − 08 | 32.75744037 | rs17716041 | 88832384 | 4 | T | G | 0.8241 | −0.05209 | 0.005529 | 4.48E − 21 | 88.75964059 | rs1805100 | 76476396 | 8 | A | G | 0.432 | 0.03729 | 0.004247 | 1.63E − 18 | 77.09394058 | rs1886603 | 119482303 | 10 | A | G | 0.3744 | 0.02607 | 0.004341 | 1.91E − 09 | 36.06637473 | rs2220970 | 9857749 | 11 | A | G | 0.3419 | 0.02475 | 0.004434 | 2.39E − 08 | 31.15724354 | rs3937435 | 113406190 | 12 | G | A | 0.3543 | −0.03648 | 0.00439 | 9.61E − 17 | 69.05269275 | rs4072037 | 155162067 | 1 | T | C | 0.8289 | −0.04491 | 0.00559 | 9.45E − 16 | 64.54498353 | rs4077450 | 79931595 | 16 | T | G | 0.5862 | −0.03561 | 0.004707 | 3.86E − 14 | 57.2341913 | rs4148155 | 89054667 | 4 | G | A | 0.2955 | 0.1136 | 0.00464 | 2.00E − 132 | 599.4054697 | rs4724828 | 1298448 | 7 | T | C | 0.4123 | 0.02793 | 0.005015 | 2.57E − 08 | 31.01701476 | rs4766566 | 111706877 | 12 | T | C | 0.6775 | 0.05443 | 0.00446 | 2.97E − 34 | 148.9384916 | rs57677015 | 10422356 | 4 | T | G | 0.1267 | 0.0725 | 0.006325 | 2.05E − 30 | 131.3877736 | rs62310009 | 89250957 | 4 | C | A | 0.1979 | 0.03427 | 0.005284 | 8.88E − 11 | 42.06322731 | rs6445559 | 53099466 | 3 | G | A | 0.4376 | −0.02594 | 0.004399 | 3.67E − 09 | 34.77218804 | rs6460047 | 73042443 | 7 | C | T | 0.106 | −0.04096 | 0.006978 | 4.38E − 09 | 34.45545312 | rs7310944 | 113045997 | 12 | A | G | 0.6318 | −0.029 | 0.004393 | 4.11E − 11 | 43.57863163 | rs73575095 | 79750332 | 16 | C | T | 0.2808 | −0.03388 | 0.004709 | 6.26E − 13 | 51.76418998 | rs7570707 | 61451744 | 2 | T | C | 0.3729 | 0.02428 | 0.00437 | 2.74E − 08 | 30.86984799 | rs7674711 | 9916180 | 4 | C | T | 0.7052 | −0.09447 | 0.004599 | 9.41E − 94 | 421.9500198 | rs7679724 | 9985376 | 4 | T | G | 0.586 | 0.1239 | 0.004284 | 5.56E − 184 | 836.4571319 | rs7835379 | 95975080 | 8 | A | G | 0.7546 | 0.0303 | 0.004928 | 7.78E − 10 | 37.80453136 | rs9394948 | 43334755 | 6 | C | A | 0.6594 | −0.03079 | 0.004536 | 1.13E − 11 | 46.0758426 | rs9416703 | 60283008 | 10 | C | A | 0.4751 | 0.03615 | 0.004289 | 3.53E − 17 | 71.04025485 | rs963837 | 30749090 | 11 | C | T | 0.3432 | −0.02785 | 0.004867 | 1.05E − 08 | 32.74369653 | rs9895661 | 59456589 | 17 | T | C | 0.4776 | 0.04506 | 0.004821 | 9.03E − 21 | 87.35909209 |
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