Lack of Association between the IL6R Gene Asp358Ala Variant (rs2228145), IL-6 Plasma Levels, and Treatment Resistance in Chilean Schizophrenic Patients Treated with Clozapine

Table 1

IL-6 plasma levels and rs2228145 genotypic and allelic frequencies for SZ patients and controls. p: p value for the comparison of each group resistance vs. remission and resistance vs. control.

	Median IL-6; plasma levels (pg/ml)	Genotypic; frequencies n (%)				Allelic; frequencies n (%)
		CC	AC	AA	p	C	A	p
Resistance	1.91	8; (34.8)	11; (43.5)	5    (21.7)		19    (47.5)	21    (52.5)
Remission	2.25	14; (36.1)	23; (55.6)	4; (8.3)	0.35	51; (62)	31    (38)	0.17
Control	N.A.	20; (42)	21; (44)	7; (15)	0.71	61    (63.5)	35    (36.4)	0.12