Research Article

Polygenic Risk Scores for Subtyping of Schizophrenia

Table 3

Change of cognitive functions between baseline and Visit 6.

Mean Diff-valuedf95% CI value

VIGILANCE
All subjects−0.30−5.31200−0.40–−0.193.0E-07
Class I−0.23−2.6479−0.40–−0.060.0099
Class II−0.24−1.4533−0.59–0.100.1578
Class III−0.41−2.9724−0.70–−0.130.0066
Class IV−0.34−2.4123−0.63–−0.050.0242
Class V−0.38−3.0337−0.63–−0.130.0045

PROCESSING SPEED
All subjects−0.24−6.45224−0.32–−0.176.8E-10
Class I−0.20−3.5687−0.31–−0.090.0006
Class II−0.29−2.8538−0.50–−0.080.0071
Class III−0.29−2.4127−0.54–−0.040.0229
Class IV−0.26−2.1726−0.51–−0.010.0395
Class V−0.25−3.2342−0.40–−0.090.0024

WORKING MEMORY
All subjects−0.20−4.27224−0.29–−0.112.8E-05
Class I−0.21−3.1487−0.34–−0.080.0023
Class II−0.18−1.3638−0.44–0.090.1819
Class III−0.09−0.5727−0.44–0.250.5740
Class IV−0.26−2.1226−0.52–−0.010.0433
Class V−0.21−2.3242−0.39–−0.030.0252

REASONING
All subjects−0.27−5.15224−0.38–−0.175.8E-07
Class I−0.28−3.2787−0.45–−0.110.0015
Class II−0.24−1.9538−0.50–0.010.0585
Class III−0.27−1.6727−0.60–0.060.1056
Class IV−0.40−2.7826−0.69–−0.100.0100
Class V−0.20−1.6642−0.44–0.040.1053

Mean Diff: mean difference between the baseline and Visit 6; 95% CI: 95% confident interval; -value: Test value; df: Degree of freedom; values ≤0.05 were highlighted in bold.