Polygenic Risk Scores for Subtyping of Schizophrenia
Table 3
Change of cognitive functions between baseline and Visit 6.
Mean Diff
-value
df
95% CI
value
VIGILANCE
All subjects
−0.30
−5.31
200
−0.40–−0.19
3.0E-07
Class I
−0.23
−2.64
79
−0.40–−0.06
0.0099
Class II
−0.24
−1.45
33
−0.59–0.10
0.1578
Class III
−0.41
−2.97
24
−0.70–−0.13
0.0066
Class IV
−0.34
−2.41
23
−0.63–−0.05
0.0242
Class V
−0.38
−3.03
37
−0.63–−0.13
0.0045
PROCESSING SPEED
All subjects
−0.24
−6.45
224
−0.32–−0.17
6.8E-10
Class I
−0.20
−3.56
87
−0.31–−0.09
0.0006
Class II
−0.29
−2.85
38
−0.50–−0.08
0.0071
Class III
−0.29
−2.41
27
−0.54–−0.04
0.0229
Class IV
−0.26
−2.17
26
−0.51–−0.01
0.0395
Class V
−0.25
−3.23
42
−0.40–−0.09
0.0024
WORKING MEMORY
All subjects
−0.20
−4.27
224
−0.29–−0.11
2.8E-05
Class I
−0.21
−3.14
87
−0.34–−0.08
0.0023
Class II
−0.18
−1.36
38
−0.44–0.09
0.1819
Class III
−0.09
−0.57
27
−0.44–0.25
0.5740
Class IV
−0.26
−2.12
26
−0.52–−0.01
0.0433
Class V
−0.21
−2.32
42
−0.39–−0.03
0.0252
REASONING
All subjects
−0.27
−5.15
224
−0.38–−0.17
5.8E-07
Class I
−0.28
−3.27
87
−0.45–−0.11
0.0015
Class II
−0.24
−1.95
38
−0.50–0.01
0.0585
Class III
−0.27
−1.67
27
−0.60–0.06
0.1056
Class IV
−0.40
−2.78
26
−0.69–−0.10
0.0100
Class V
−0.20
−1.66
42
−0.44–0.04
0.1053
Mean Diff: mean difference between the baseline and Visit 6; 95% CI: 95% confident interval; -value: Test value; df: Degree of freedom; values ≤0.05 were highlighted in bold.