Research Article

Polygenic Risk Scores for Subtyping of Schizophrenia

Table 4

Changes of laboratory tests between baseline and end of Phase I trial.

Mean Diff-valuedf95% CI value

HDL
All subjects−0.07−0.15419−0.99–0.850.8833
Class I−2.25−3.04168−3.70–−0.790.0027
Class II−0.68−0.6178−2.90–1.530.5406
Class III2.941.9849−0.05–5.930.0537
Class IV1.931.5543−0.57–4.440.1274
Class V2.222.30770.30–4.130.0239

Calcium
All subjects0.083.614190.04–0.120.0003
Class I0.051.28168−0.02–0.130.2041
Class II0.081.8077−0.01–0.180.0763
Class III0.071.1050−0.06–0.210.2757
Class IV0.121.7943−0.02–0.260.0806
Class V0.142.71770.04–0.240.0084

Phosphorus
All subjects0.102.994190.04–0.170.0029
Class I0.020.41168−0.09–0.140.6858
Class II0.121.4977−0.04–0.280.1409
Class III0.192.26500.02–0.370.0282
Class IV0.161.5443−0.05–0.380.1318
Class V0.172.25770.02–0.320.0276

Lymphocytes
All subjects0.230.55416−0.58–1.040.5806
Class I0.671.06164−0.58–1.900.2915
Class II0.680.6878−1.11–2.470.4531
Class III−0.14−0.1252−2.53–2.250.9084
Class IV−3.12−2.8643−5.32–−0.920.0065
Class V1.000.9075−1.21–3.210.3684

Neutrophils
All subjects−0.48−1.02416−1.40–0.440.3092
Class I−0.96−1.42164−2.30–0.380.1588
Class II−0.98−0.9178−3.12–1.160.3660
Class III0.340.2352−2.58–3.260.8161
Class IV3.042.39430.47–5.610.0214
Class V−1.51−1.2275−3.97–0.960.2265

Mean Diff: mean difference between the baseline and Phase I; 95% CI: 95% confidence interval; -value: test value; df: degree of freedom; values ≤0.05 were highlighted by bold; HDL: high-density lipoproteins.