Research Article
Reducing TRPC1 Expression through Liposome-Mediated siRNA Delivery Markedly Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension in a Murine Model
Table 2
Baseline characteristics of three group animals at day 28 after hypoxia-induced pulmonary arterial hypertension.
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Data are expressed as means ± SD. RBC = red blood cell; RVSP = right ventricular systolic pressure; LVSBP = left ventricular systolic blood pressure; HW = heart weight. Group 1 = sham control; group 2 = hypoxia + negative control siRNA; group 3 = hypoxia + siRNA-TRPC1. *By one-way ANOVA. Different letters (a, b, c) are being used for grouping, showing significant difference (at level 0.05) among different groups by Tukey’s multiple comparison procedure. |