Research Article
Contribution of Mouse Embryonic Stem Cells and Induced Pluripotent Stem Cells to Chimeras through Injection and Coculture of Embryos
Table 2
Generation of chimeric mice with ESCs.
| Method |
Number of embryos transferred |
Number of recipients |
Number of pregnant recipients (%) |
Number of pups |
Number of chimeras (%) | Total | Full colored |
| 8-cell coculture | 312 | 14 | 11 (78.6)a | 86 | 25 (29.1)ab | 3 (12.0)a | 8-cell injection | 365 | 17 | 14 (82.4)a | 127 | 23 (18.1)a | 1 (4.3)a | Blastocyst injection | 129 | 6 | 6 (100)a | 73 | 28 (38.4)b | 0 (0.0)a |
| Total | 806 | 37 | 31 (83.8) | 286 | 76 (26.6) | 4 (1.4) |
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Values with different superscripts within the same column are significantly different ().
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