Topical Application of bFGF Alone for the Regeneration of Chronic Tympanic Membrane Perforations: A Preliminary Case Series

Figure 1

(Patient 1): a 37-year-old woman with COM and a left medium-sized perforation. Pretreatment perforation (a), freshened edges (b), and edges after 2 (c), 7 (d), and 12 (e) weeks of treatment. Red arrows indicate a moderate granulation reaction.

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(b)

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(e)